Dr. Robert H. Keller, the creator of MaxGXL and a pioneer in glutathione research, served on the scientific review panels for the National Institutes of Health and the VA. The Consumers' Research Council named him one of America's Top Physicians in 2003, 2004, 2005, 2006, and 2007 in the fields of Internal Medicine, Immunology and Hematology. Dr. Keller also served on the faculties of the Mayo Graduate School of Medicine, the University of Wisconsin and the Medical College of Wisconsin (Marquette Univ.) He published more than 100 original articles in various scientific and medical journals and was awarded several patents. Additionally, Dr. Keller was elected to The Board of Governors of the American Academy of HIV Medicine.m a paragraph. Click here to add your own text and edit me. I’m a great place for you to tell a story and let your users know a little more about you.
Education and Training:
1966 Bachelor of Arts
Master of Science in Biology
Fordham University, Bronx, New York
1970 Doctor of Medicine (MD) with honors
Temple University, Philadelphia, Pennsylvania
1970-1974 Internship, Resident and Senior Resident
University of Rochester, Rochester, New York
1974-1976 Fellow and Senior Fellow
Department of Immunology
Mayo Clinic, Rochester Minnesota
1976 Master of Science in Immunology
Mayo Graduate School of Medicine
Rochester, Minnesota
Professional Experience:
1974-1977 Fellow and Senior Research Fellow in Immunology
Mayo Clinic Foundation
Mayo Graduate School of Medicine
1977 Consultant and Assistant Professor
Department of Immunology
Mayo Medical School
Dept. of Medicine
1980-1982 Director of Immunology
Midwest Children’s Cancer Center
Associate Professor
Department of Pediatrics
1982-1986 Clinical Professor
Department of Health Sciences
(Hematology, Immunology, Flow Cytometry)
University of Wisconsin
THE PRIMARY CREATOR OF RIBOCEINE
Dr. Herbert T. Nagasawa received his B.S. degree in chemistry from Western Reserve University (now, Case-Western Reserve) in Cleveland, Ohio, and a Ph.D. degree in organic chemistry from the University of Minnesota. Subsequently, he spent two years as a Post-doctoral Fellow in biochemistry at the University of Minnesota before joining the research staff of the V.A. Medical Center in Minneapolis as a Senior Chemist. He was appointed Assistant Professor of Medicinal Chemistry at the University of Minnesota in 1959. He was named Principal Scientist of the VAMC in 1961 and was promoted in 1976 to Senior Research Career Scientist, a nationwide VA title reserved for the VA's top scientists. He was promoted to Associate Professor in 1963 and to Professor of Medicinal Chemistry in 1973.
He also held joint professorships in the Department of Pharmacology and the university-wide Division of Toxicology, and served as Visiting Professor at Washington State University in 1990. He also served for 32 years as a Senior Editor for the prestigious international Journal of Medicinal Chemistry from 1972 to 2004, and one year as Acting Editor-in-Chief. In addition, he served on the Editorial Board of the journal, Bioconjugate Chemistry for eight years, and as an ad hoc grant reviewer for the NCI and NIAAA, National Institutes of Health. He has published over 165 papers in peer-reviewed journals. In June of 2010, Dr. Nagasawa and his team attended the National Institutes of Health-Homeland Security 4th Annual Countermeasures Against Chemical Threats Network Symposium to present their work on the cyanide antidote.
CURRICULUM VITAE
Name: Herbert T. Nagasawa
Place of Birth: Hilo, Hawaii
Education:
B.S. 1950 Western Reserve University, Cleveland, OH
Major: Chemistry
Minor: Mathematics
Honors: Phi Society (Honorary Scholastic)
Ph.D. 1955 University of Minnesota, Minneapolis, MN
Major: Organic Chemistry
Minor: Analytical Inorganic and Physical Chemistry
Honors: Phi Lambda Upsilon (Chemistry Scholastic)
Post-Doctoral 1955- Department of Biochemistry, University of Minnesota,
Fellow 1957 Minneapolis, MN
Honors: Sigma Xi (Scientific Research)
Military Service:
1945 - 1947 Military Intelligence Service, U.S. Army Positions Held:
1951 - 1954 Teaching Assistant, Department of Chemistry, University of
Minnesota, Minneapolis, MN
1954 - 1955 Pre-doctoral Fellow, Allied Chemical & Dye Corp., Department of
Chemistry, University of Minnesota, Minneapolis, MN
1955 - 1957 Post-doctoral Fellow, Department of Biochemistry, University of
Minnesota, Minneapolis, MN
1957-1961 Senior Chemist, Radioisotope Service Research Laboratory,
Veterans Administration Medical Center, Minneapolis, MN
1961-1978 Senior Scientist, Laboratory for Cancer Research, Veterans
Administration Medical Center, Minneapolis, MN
1961 - 1976 Principal Scientist, General Medical Research, Veterans
Administration Medical Center, Minneapolis, MN
1961 - 1981 Member and Basic Science Representative, Research and
Education Committee, Veterans Administration Medical Center, Minneapolis, MN
"Committed to develop real health breakthroughs based on scientific research that will lead the wellness and nutritional industry to deliver total quality proprietary products through the efforts and labor of renowned medicinal chemist Dr. Herbert T. Nagasawa and other world experts who made groundbreaking advances in glutathione enhancing products."
1978 - 2002 Senior Research Career Scientist, Veterans Administration
MedicalCenter, Minneapolis, MN
2002 - 2004 Senior Medical Research Scientist, Veterans Administration
Medical Center, Minneapolis, MN 1959 - 1963 Assistant Professor, Pharmaceutical Chemistry, University of Minnesota, Minneapolis, MN
1963 - 1972 Associate Professor, Medicinal Chemistry, University of Minnesota,
Minneapolis, MN
1973 - 2004 Professor, Medicinal Chemistry, University of Minnesota,
Minneapolis, MN (Officially retired 6/04)
1987 - 1995 Professor, Pharmacology, University of Minnesota, Minneapolis, MN
1990 - 2004 Professor, Toxicology, University of Minnesota, Duluth, MN
(Officially retired 6/04)
2004-2007 Member, Center for Drug Design, Academic Health Center,
University of Minnesota
2007-to date Adjunct Professor, Center for Drug Design, Academic Health
Center, University of Minnesota
1972 - 1984 Associate Editor, Journal of Medicinal Chemistry, American
Chemical Society (Acting Editor: 8/73 to 6/74)
1985 - 2004 Senior Editor, Journal of Medicinal Chemistry, American Chemical
Society (Retired 6/04)
1974 - 1977 Member, Health Sciences Policy and Review Council, University of
Minnesota Graduate School, Minneapolis, MN
1976 - 1978 Chairperson, Biomedical Research Committee, Alcohol and Other
Drub Abuse Program (AODAP), University of Minnesota, Minneapolis, MN
1983 - 1984 AODAP Biomedical Grants Review Committee, University of
Minnesota, Minneapolis, MN
1980 - 1981 Ad Hoc Member, Initial Review Group (IRG), Biomedical Research
Review Committee, Alcohol, Drug Abuse and Mental Health
Administration (ADAMHA)
1984 - 1985 Member, Special Review Committee, "National Cooperative Drug
Discovery Group (NCDDG)", National Cancer Institute, National
Institutes of Health (NIH)
1985 Judge, Third Annual Graduate Student Awards, Mechanisms
Section, Society of Toxicology
1990 Visiting Professor, College of Pharmacy, Washington State
University, Pullman, WA (March 24-31)
1990 - 1997 Editorial Board, Bioconjugate Chemistry, American Chemical Society
Professional Societies:
American Academy of Anti-Aging Medicine (A4M)
American Chemical Society (ACS)
American Society for Pharmacology and Experimental Therapeutics (ASPET)
American Association for Cancer Research (AACR)
American Association for the Advancement of Science (AAAS) International Society for Biomedical Research on Alcoholism (ISBRA)
International Society for the Study of Xenobiotics (ISSX)
New York Academy of Sciences (NYAS): Elected as Fellow, 1983
Research Society on Alcoholism (RSA)
Society of Toxicology (SOT)
Nitric Oxide Society
Listed: American Men and Women of Science; Who's Who in the Midwest
Graduate Faculty Appointment:
Medicinal Chemistry: B Appointment (Full Member)
Pharmacology: A Appointment (Associate Member)
Toxicology: B Appointment (Full Member)
Research Interests:
Design and synthesis of a) trapping agents for the detoxification of xenobiotic substances that are activated to toxic metabolites in vivo, b) latentiated (prodrug) forms of biologically active substances such as nitroxyl (HNO), c) prodrugs of cysteine and glutathione as protective agents for cellullar oxidative stress, and d) cyanide antidotes based on β-mercaptopyruvate.
Hospital Staff Appointments:
1976-1977 Mayo Clinic, Rochester, Minnesota
1977-1986 Zablocki VAMC, Milwaukee, Wisconsin
1977-1986 Milwaukee County Medical Complex, Milwaukee, Wisconsin
1992-1997 Mount Sinai Medical Center, Miami Beach, Florida
1992-1999 Cleveland Clinic Hospital, Fort Lauderdale, Florida
1992-1999 Miami Heart Institute, Miami Beach, Florida
1997-1999 Palmetto General Hospital, Hialeah, Florida
1997-2005 South Short Hospital, Miami Beach, Florida
1997-2005 Memorial Medical Center, Hollywood, Florida
1992-present Broward General Medical Center, Fort Lauderdale, Florida
1997-present Hollywood Medical Center, Hollywood, FloridaFellowships and Awards:
1974-1975 Mayo Foundation Research Fellowship
Mayo Graduate School of Medicine
1978-1981 VA Career Development Award, Research Associate
1983-1986 VA Career Development Award, Clinical Investigator
Honors:
1970 Medical Degree with honors
Temple University, School of Medicine
2001-present 2000 Outstanding Scientists of the 21st Century
2002- present 1000 Great Americans of the 21st Century
2003-present America’s Top Physicians in Internal Medicine, Immunology and
Hematology by Consumer’s Research Council
2004-present Elected to Board of Governor’s
Academy of HIV Medicine of the State of Florida
Board of Director Appointments:
2006-present Member American Academy of HIV Medicine
Certifications:
National Board of Medical Examiners, 1971 and 1990
American Board of Internal Medicine, 1974-present
American Academy of HIV Medicine, 2001- present
American Academy of Anti-Aging Medicine, 2006-present
Review Board:
National Institutes of Health 1983-1986
Mount Sinai Medical Center 1994-1997
Hollywood Medical Center 2001-present